The end-to-end RYZ-101 workflow.
From the first multidisciplinary review through cycle planning and follow-up — a practical view of the workflow centers will operate when delivering RYZ-101.
Eight steps, one continuous patient journey
- 01
Referral & eligibility
Multidisciplinary review of imaging, prior therapy, organ function, and SSTR-expression status to confirm candidacy.
Patient identification → - 02
Multidisciplinary planning
Nuclear medicine, medical oncology, pharmacy, and nursing align on dosing schedule, supportive care, and monitoring plan.
MDT care model → - 03
Informed consent
Discussion of expected benefits, risks specific to alpha therapy, radiation safety precautions, and logistical considerations for the patient and household.
- 04
Dose preparation & QC
Unit dose receipt, identity and activity verification, and final QC in the hot lab prior to administration.
- 05
Administration
IV administration in a shielded chair per institutional protocol, with concurrent supportive care (e.g. amino acid co-infusion where indicated).
- 06
Post-administration monitoring
Vital signs, acute reaction monitoring, and contamination check prior to discharge from the administration suite.
- 07
Discharge & home precautions
Patient-specific radiation safety instructions, household contact guidance, and clear escalation pathway for adverse events.
- 08
Follow-up & cycle planning
Lab and imaging follow-up, AE assessment, and scheduling of subsequent cycles per protocol.